Endometrial dating histology

ENDOMETRIUM, ASPIRATION: - ENDOMETRIAL GLANDS WITH APOPTOTIC CELLS, INFILTRATING NEUTROPHILS, AND GLANDULAR PROLIFERATIVE ACTIVITY. - SCANT STRIPPED ENDOCERVICAL EPITHELIUM WITHIN NORMAL LIMITS. COMMENT: The findings are most in keeping with late menstrual endometrium.

ENDOMETRIUM, BIOPSY: - BENIGN ADIPOSE TISSUE, SEE COMMENT. COMMENT: The presence of adipose tissue raises the possibility of perforation.

- SMALL FRAGMENTS OF DETACHED BENIGN SQUAMOUS EPITHELIUM.

COMMENT: A re-biopsy should be considered within the clinical context.

Tissue from the fundus of the uterus gives the most reliable information.

These critera were used in 300 sterility biopsies taken from normally menstruating women over a 3-year period.

ENDOMETRIUM, BIOPSY: - FRAGMENTS OF DETACHED SQUAMOUS EPITHELIUM, ENDOCERVICAL EPITHELIUM AND FOCALLY PROLIFERATIVE ENDOMETRIAL GLANDS.

- ASSESSMENT LIMITED AS NO DEFINITE ENDOMETRIAL STROMA IS PRESENT.

During the 1st week of luteal activity, attention should be focused on changes occurring in gland epithelium: gland mitosis, pseudostratification of nuclei, basal vacuolation, and secretion.

During the 2nd week , stromal changes (including edema), predecidual reaction, stromal mitosis, and leukocytic infiltration are the key criteria.

Of the 40 patients who had adequate temperature records, 31 (78%) ovulated as predicted allowing a or- 1 day error, indicating that dating is a better gauge of duration of progesterone effect than predictor of onset of menses.

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