Sedating affect

Caution is therefore required when such agents are prescribed for patients with receive hypnotics, sedatives and opiates/opioids to treat conditions including pain, anxiety and difficulty sleeping.Concerns have been expressed that administration of these drugs to people with co-existing .Virtually all of the sedative, hypnotic and anxiolytic agents bind to GABA moieties at the benzodiazepine receptor.

Concern has been raised over the use of any sedative while still on a plane, as a sedated sleeper may be less mobile and more prone to deep venous thrombosis (the same, of course, applies to alcohol). and narcotics have a propensity to exacerbate the sleep-related apneic episodes and may impair life-saving arousal in patients with OSAHS.

The AAMS guidelines recommend the short-term use of should be avoided in view of the multiple systemic complications of hypopituitarism, and the risk of respiratory depression. Benzodiazepines and barbiturates preferentially decrease neural input to the upper airway dilating muscles, leading to airway obstruction. Anxiolytic drugs such as midazolam should only be administered when close monitoring of the patient by appropriate personnel is possible.

In these cases the sedative should be combined with an opioid analgesic, a practice termed neuroleptanalgesia.

Such combinations have a number of advantages and their use is to be recommended even in the nonpainful patient.

Their use renders the patient more tractable, thereby improving staff safety and assisting the placement of intravenous catheters. By reducing fear and anxiety prior to induction of anesthesia, the potential for catecholamine-induced dysrhythmias is reduced.

Generally, the quality of anesthetic induction and recovery is improved by , there being less risk of excitement.

(However, Chloral hydrate has been discontinued in the US.) Excessive doses result in hypersomnia.

Respiratory depression can occur when combined with other The medication is no longer available because of a production shortage, and clinicians are faced with a challenge of finding suitable alternatives, especially because it is widely used for sedated procedures in pediatrics.

Glycopyrrolate to reduce oral secretions and dexametasone to reduce airway edema and nausea and vomiting are generally administered.

and analgesics are frequently administered to patients in the ICU to provide pain relief for pre- and postsurgical procedures, promote relaxation, relieve anxiety and physical stress, induce sleep, and reduce mobility and agitation. These drugs may also be utilized for analgesia, in addition to nonsteroidal antiinflammatory antibodies.

Long-term use has been reported in children with neurodevelopmental disabilities. Notable effects of this class of medication include: reduced anxiety, anterograde amnesia, and sedation as well as memory impairment.

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